Reaction Details Report a problem with these data
Target
G-protein coupled receptor 4
Ligand
BDBM123494
Substrate
n/a
Meas. Tech.
Radio Ligand Binding Assay
pH
8±n/a
IC50
54±n/a nM
Citation
 Miltz, W; Oberhauser, B; Vaupel, A; Velcicky, J; Weigand, K; Leleti, RR; Liu, Y; Du, Z Pyrazolo pyrimidine derivatives US Patent  US8748435 Publication Date 6/10/2014 
Target
Name:
G-protein coupled receptor 4
Synonyms:
G-protein coupled receptor 4 | G-protein coupled receptor 4 (GPR4) | GPR4 | GPR4_HUMAN
Type:
Enzyme
Mol. Mass.:
40994.40
Organism:
Human
Description:
P46093
Residue:
362
Sequence:
MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPPAQ
  
Inhibitor
Name:
BDBM123494
Synonyms:
US8748435, 19
Type:
Small organic molecule
Emp. Form.:
C29H39N5O3
Mol. Mass.:
505.6517
SMILES:
CCc1nn2c(C)cc(C)nc2c1Cc1ccc(CCC(=O)N2CCN(CC2)C(=O)OC(C)(C)C)cc1
Structure:
Search PDB for entries with ligand similarity: