Reaction Details Report a problem with these data
Target
S-methyl-5'-thioinosine phosphorylase
Ligand
BDBM50247149
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.4±n/a
Temperature
298.15±n/a K
Ki
0.076±n/a nM
Comments
extracted
Citation
Schramm, VL; Clinch, K; Tyler, PC; Evans, GB; Furneaux, RH Methods, assays and compounds for treating bacterial infections by inhibiting methylthioinosine phosphorylase US Patent US9290501 Publication Date 3/22/2016
More Info.:
Target
Name:
S-methyl-5'-thioinosine phosphorylase
Synonyms:
MTIP_PSEAE | S-methyl-5'-thioinosine phosphorylase (MTIP)
Type:
Enzyme
Mol. Mass.:
26266.70
Organism:
Pseudomonas aeruginosa
Description:
Q9HZK1
Residue:
245
Sequence:
MSVYAIIGGTGLTQLEGLTLSESLPIETPYGAPSAPLQRGRYAGREVLFLARHGHPHRFPPHQVNYRANLWALKQAGAEAVIAVNAVGGIHAAMGTGHLCVPHQLIDYTSGREHTYFAGDIEHVTHIDFSHPYDEPLRQRLIEALRALGLAHSSHGVYACTQGPRLETVAEIARLERDGNDIVGMTGMPEAALARELDLPYACLALVVNPAAGKSAGIITMAEIEQALHDGIGKVREVLARVLAG