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Target
Casein kinase I isoform delta
Ligand
BDBM50537608
Substrate
n/a
Meas. Tech.
Kinase Assays
IC50
2989±n/a nM
Citation
 Arancio, O; Watterson, DM; Pelletier, JC; Roy, SM MAP kinase modulators and uses thereof US Patent  US11149020 Publication Date 10/19/2021 
Target
Name:
Casein kinase I isoform delta
Synonyms:
CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta)
Type:
Enzyme
Mol. Mass.:
47356.76
Organism:
Human
Description:
P48730
Residue:
415
Sequence:
MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
  
Inhibitor
Name:
BDBM50537608
Synonyms:
CHEMBL4639995 | US11149020, Compound 32 (MW-148)
Type:
Small organic molecule
Emp. Form.:
C23H20N4
Mol. Mass.:
352.4317
SMILES:
C1CCN(C1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1
Structure:
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