Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM350626
Substrate
n/a
Meas. Tech.
FLIPR
EC50
7900±n/a nM
Citation
 Beard, RL; Donello, JE; Viswanath, V Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases US Patent  US10208071 Publication Date 2/19/2019 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM350626
Synonyms:
1-(4-bromophenyl)-3-{4- methyl-2,5-dioxo-4-[2- (thiophen-2- yl)ethyl]imidazolidin-1-yl}urea | US10208071, Compound 88 | US10434112, Compound 88 | US10799518, Compound 88
Type:
Small organic molecule
Emp. Form.:
C17H17BrN4O3S
Mol. Mass.:
437.311
SMILES:
CC1(CCc2cccs2)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O
Structure:
Search PDB for entries with ligand similarity: