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Target
Procathepsin L
Ligand
BDBM41173
Substrate
n/a
Meas. Tech.
Cathepsin L dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin L dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM41173
Synonyms:
2-(4-ethoxyanilino)-6-oxo-N-(phenylmethyl)-4,5-dihydro-1H-pyrimidine-4-carboxamide | 2-[(4-ethoxyphenyl)amino]-6-oxidanylidene-N-(phenylmethyl)-4,5-dihydro-1H-pyrimidine-4-carboxamide | MLS000097362 | N-benzyl-2-(4-ethoxyanilino)-6-oxo-4,5-dihydro-1H-pyrimidine-4-carboxamide | N-benzyl-2-[(4-ethoxyphenyl)amino]-6-oxo-1,4,5,6-tetrahydro-4-pyrimidinecarboxamide | N-benzyl-6-keto-2-(p-phenetidino)-4,5-dihydro-1H-pyrimidine-4-carboxamide | SMR000075989 | cid_2952291
Type:
Small organic molecule
Emp. Form.:
C20H22N4O3
Mol. Mass.:
366.4137
SMILES:
CCOc1ccc(NC2=NC(CC(=O)N2)C(=O)NCc2ccccc2)cc1 |t:8|
Structure:
Search PDB for entries with ligand similarity: