Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50001514
Substrate
n/a
Meas. Tech.
ChEBML_28843
Ki
15000±n/a nM
Citation
 Daly, JW; Padgett, WL; Shamim, MT Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors. J Med Chem 29:1305-8 (1987) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50001514
Synonyms:
1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione | CHEMBL24107
Type:
Small organic molecule
Emp. Form.:
C8H10N4O2
Mol. Mass.:
194.1906
SMILES:
CCn1c(=O)n(C)c2nc[nH]c2c1=O
Structure:
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