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Target
Translocator protein
Ligand
BDBM50588818
Substrate
n/a
Meas. Tech.
ChEMBL_2191890 (CHEMBL5104250)
EC50
39000±n/a nM
Citation
 Barresi, E; Robello, M; Costa, B; Da Pozzo, E; Baglini, E; Salerno, S; Da Settimo, F; Martini, C; Taliani, S An update into the medicinal chemistry of translocator protein (TSPO) ligands. Eur J Med Chem 209:0 (2021) [PubMed] 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Human
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50588818
Synonyms:
CHEMBL5174807
Type:
Small organic molecule
Emp. Form.:
C23H25Cl2N3O4
Mol. Mass.:
478.368
SMILES:
CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(OCC(O)=O)cc1
Structure:
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