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Target
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Ligand
BDBM50355115
Substrate
n/a
Meas. Tech.
ChEMBL_772123 (CHEMBL1838042)
IC50
13000±n/a nM
Citation
Tang, M; Odejinmi, SI; Allette, YM; Vankayalapati, H; Lai, K Identification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDP-ME) kinase of Gram-negative bacteria. Bioorg Med Chem 19:5886-95 (2011) [PubMed] Article
More Info.:
Target
Name:
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Synonyms:
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase | CMK | ISPE_YERPE | ipk | ispE
Type:
PROTEIN
Mol. Mass.:
32675.02
Organism:
Yersinia pestis
Description:
ChEMBL_772123
Residue:
299
Sequence:
MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQIRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAATVLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVIHPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYAPSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR