Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50005494
Substrate
n/a
Meas. Tech.
ChEBML_138664
IC50
310±n/a nM
Citation
Sowell, JW; Tang, Y; Valli, MJ; Chapman, JM; Usher, LA; Vaughan, CM; Kosh, JW Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine. J Med Chem 35:1102-8 (1992) [PubMed] Article
More Info.:
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_MOUSE | Cholinergic receptor, muscarinic 1, CNS | Cholinergic, muscarinic | Chrm-1 | Chrm1 | Muscarinic acetylcholine receptor | Muscarinic acetylcholine receptor M1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51400.50
Organism:
Mouse
Description:
Cholinergic, muscarinic 0 0::Q52KQ0
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC