Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50415881
Substrate
n/a
Meas. Tech.
ChEMBL_629913 (CHEMBL1108377)
Ki
2511.89±n/a nM
Citation
 Areias, FM; Brea, J; Gregori-Puigjané, E; Zaki, ME; Carvalho, MA; Domínguez, E; Gutiérrez-de-Terán, H; Proença, MF; Loza, MI; Mestres, J In silico directed chemical probing of the adenosine receptor family. Bioorg Med Chem 18:3043-52 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50415881
Synonyms:
CHEMBL1097859
Type:
Small organic molecule
Emp. Form.:
C21H22N4O
Mol. Mass.:
346.4256
SMILES:
Cc1ccc(cc1)-c1nc(C(=O)Nc2ccccn2)c2CCCCCn12
Structure:
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