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Found 86 with Last Name = 'mestres' and Initial = 'j'
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50415880(CHEMBL1097489)
Affinity DataKi:  15.8nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 60 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataKi:  25.1nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)
Affinity DataKi:  31.6nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataKi:  63.1nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386103(CHEMBL1990267)
Affinity DataKi:  79.4nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataKi:  100nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386110(CHEMBL2042073)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50415880(CHEMBL1097489)
Affinity DataKi:  158nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in forskolin-stimulated CHO cells assessed as inhibition of NSCA-induced decrease in cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386103(CHEMBL1990267)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50415879(CHEMBL1099202)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in human HeLa cells after 180 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386106(CHEMBL2042091)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386113(CHEMBL2042061)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386105(CHEMBL2042058)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386103(CHEMBL1990267)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 60 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386115(CHEMBL2042059)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386117(CHEMBL2042062)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386112(CHEMBL2042060)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386104(CHEMBL2042077)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386111(CHEMBL2042072)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50415879(CHEMBL1099202)
Affinity DataKi:  501nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in forskolin-stimulated CHO cells assessed as inhibition of NSCA-induced decrease in cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386107(CHEMBL2042081)
Affinity DataKi:  631nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386110(CHEMBL2042073)
Affinity DataKi:  631nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386118(CHEMBL2042074)
Affinity DataKi:  631nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386111(CHEMBL2042072)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386108(CHEMBL2042076)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386116(CHEMBL2042080)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386109(CHEMBL2042075)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386106(CHEMBL2042091)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386109(CHEMBL2042075)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386114(CHEMBL2042069)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50415878(CHEMBL1095872)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50415878(CHEMBL1095872)
Affinity DataKi:  2.00E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in HEK293 cells assessed as inhibition of NSCA-induced cAMP accumulation pre-incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386113(CHEMBL2042061)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 60 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386106(CHEMBL2042091)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 60 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50415881(CHEMBL1097859)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50415881(CHEMBL1097859)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in human HeLa cells after 180 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386105(CHEMBL2042058)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 60 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNischarin(Homo sapiens (Human))
Imim-Hospital Del Mar Research Institute And University Pompeu Fabra

Curated by ChEMBL
LigandPNGBDBM50399449(CHEMBL2179395)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of radioligand binding to imidazole receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386104(CHEMBL2042077)
Affinity DataKi:  6.31E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 60 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50415881(CHEMBL1097859)
Affinity DataKi:  7.94E+3nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NSCA-induced cAMP accumulation pre-incubated for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386112(CHEMBL2042060)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386113(CHEMBL2042061)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universidade Do Minho

Curated by ChEMBL
LigandPNGBDBM50386115(CHEMBL2042059)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417668(CHEMBL1643368)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataKi:  2.51E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)
Affinity DataKi:  7.94E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417683(CHEMBL1643573)
Affinity DataIC50:  240nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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