Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50415881
Substrate
n/a
Meas. Tech.
ChEMBL_629909 (CHEMBL1108373)
Ki
3162.28±n/a nM
Citation
 Areias, FM; Brea, J; Gregori-Puigjané, E; Zaki, ME; Carvalho, MA; Domínguez, E; Gutiérrez-de-Terán, H; Proença, MF; Loza, MI; Mestres, J In silico directed chemical probing of the adenosine receptor family. Bioorg Med Chem 18:3043-52 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50415881
Synonyms:
CHEMBL1097859
Type:
Small organic molecule
Emp. Form.:
C21H22N4O
Mol. Mass.:
346.4256
SMILES:
Cc1ccc(cc1)-c1nc(C(=O)Nc2ccccn2)c2CCCCCn12
Structure:
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