Reaction Details Report a problem with these data
Target
Metallo-beta-lactamase VIM-2
Ligand
BDBM580196
Substrate
n/a
Meas. Tech.
Single Dose Enzymatic Inhibition Assay
Ki
13.0±n/a nM
Citation
 Sham, YY; Muthyala, R; Shin, W Therapeutic methods and combinations US Patent  US11491146 Publication Date 11/8/2022 
Target
Name:
Metallo-beta-lactamase VIM-2
Synonyms:
Beta-lactamase VIM-2 | Metallo-beta-lactamase VIM-2 (VIM-2)
Type:
Protein
Mol. Mass.:
28318.00
Organism:
Pseudomonas aeruginosa (g-Proteobacteria)
Description:
n/a
Residue:
266
Sequence:
MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRSVVE
  
Inhibitor
Name:
BDBM580196
Synonyms:
US11491146, Compound 3
Type:
Small organic molecule
Emp. Form.:
C7H7NO2S
Mol. Mass.:
169.201
SMILES:
CC(=O)c1cccc(=S)n1O
Structure:
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