Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM350519
Substrate
n/a
Meas. Tech.
FLIPR
EC50
152000±n/a nM
Citation
 Beard, RL; Donello, JE; Viswanath, V Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases US Patent  US10208071 Publication Date 2/19/2019 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM350519
Synonyms:
(2S)-2-({[(4-bromo-2- fluorophenyl)amino]carbonyl}amino)- 3-methylbutanoic acid | US10208071, Table 1.16 | US10434112, Table 1.16 | US10799518, Structure TABLE 1.16
Type:
Small organic molecule
Emp. Form.:
C12H14BrFN2O3
Mol. Mass.:
333.154
SMILES:
CC(C)[C@H](NC(=O)Nc1ccc(Br)cc1F)C(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: