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Target
Isoform Short of Probable global transcription activator SNF2L2 (Short) 377-1486]
Ligand
BDBM394456
Substrate
n/a
Meas. Tech.
BRM SM TR-FRET Binding Assay
IC50
35.6±n/a nM
Citation
 Albrecht, BK; Cote, A; Crawford, T; Duplessis, M; Good, AC; LeBlanc, Y; Magnuson, SR; Nasveschuk, CG; Romero, FA; Tang, Y; Taylor, AM Therapeutic compounds and uses thereof US Patent  US10308614 Publication Date 6/4/2019 
Target
Name:
Isoform Short of Probable global transcription activator SNF2L2 (Short) 377-1486]
Synonyms:
ATP-dependent helicase SMARCA2 | BAF190B | BRM | BRM (Isoform 2) Bromodomain1377-1486 | P51531-2(S1377-Q1486) | Probable global transcription activator SNF2L2 | Probable global transcription activator SNF2L2 (Short) [1377-1486] | SMARCA2 | SMCA2_HUMAN | SNF2A | SNF2L2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12874.68
Organism:
Homo sapiens (Human)
Description:
P51531-2 aa 1377-1486
Residue:
110
Sequence:
SPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQ
  
Inhibitor
Name:
BDBM394456
Synonyms:
2-(6-amino-5-(3- | US10308614, Example 57
Type:
Small organic molecule
Emp. Form.:
C19H18N4O2
Mol. Mass.:
334.3718
SMILES:
Nc1nnc(cc1N1CC(C1)Oc1ccccc1)-c1ccccc1O
Structure:
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