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Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42199
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
41272.81952±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42199
Synonyms:
(4-methoxyphenyl)-[5-[(4-methoxyphenyl)iminomethyl]-3-methyl-1-(2-pyridyl)-6,7-dihydroindazol-4-yl]amine | MLS000594510 | N-(4-methoxyphenyl)-5-[(4-methoxyphenyl)iminomethyl]-3-methyl-1-(2-pyridinyl)-6,7-dihydroindazol-4-amine | N-(4-methoxyphenyl)-5-[(4-methoxyphenyl)iminomethyl]-3-methyl-1-pyridin-2-yl-6,7-dihydroindazol-4-amine | N-[5-[(4-methoxyanilino)methylene]-3-methyl-1-(2-pyridinyl)-6,7-dihydro-1H-indazol-4-ylidene]-N-(4-methoxyphenyl)amine | SMR000115598 | cid_991147
Type:
Small organic molecule
Emp. Form.:
C28H27N5O2
Mol. Mass.:
465.5463
SMILES:
COc1ccc(NC2=C(CCc3c2c(C)nn3-c2ccccn2)C=Nc2ccc(OC)cc2)cc1 |w:24.27,t:7|
Structure:
Search PDB for entries with ligand similarity: