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Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM67430
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
725.27±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM67430
Synonyms:
2-methyl-5-[(4-methylphenyl)sulfonylamino]-N-phenyl-3-benzo[g]benzofurancarboxamide | 2-methyl-5-[(4-methylphenyl)sulfonylamino]-N-phenyl-benzo[g][1]benzofuran-3-carboxamide | 2-methyl-5-[(4-methylphenyl)sulfonylamino]-N-phenylbenzo[g][1]benzofuran-3-carboxamide | 2-methyl-N-phenyl-5-(tosylamino)benzo[g]benzofuran-3-carboxamide | MLS000394360 | SMR000248371 | cid_2337760
Type:
Small organic molecule
Emp. Form.:
C27H22N2O4S
Mol. Mass.:
470.54
SMILES:
Cc1oc2c(cc(NS(=O)(=O)c3ccc(C)cc3)c3ccccc23)c1C(=O)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: