Reaction Details Report a problem with these data
Target
Female germline-specific tumor suppressor gld-1
Ligand
BDBM67433
Substrate
n/a
Meas. Tech.
Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction
IC50
15120±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Female germline-specific tumor suppressor gld-1
Synonyms:
GLD1_CAEEL | defective in Germ Line Development family member (gld-1) | gld-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50591.33
Organism:
Caenorhabditis elegans
Description:
gi_17507875
Residue:
463
Sequence:
MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF
  
Inhibitor
Name:
BDBM67433
Synonyms:
MLS001004132 | N-(6-methoxy-3-pyridinyl)-2-phenylacetamide | N-(6-methoxy-3-pyridyl)-2-phenyl-acetamide | N-(6-methoxypyridin-3-yl)-2-phenyl-ethanamide | N-(6-methoxypyridin-3-yl)-2-phenylacetamide | SMR000377800 | cid_16196270
Type:
Small organic molecule
Emp. Form.:
C14H14N2O2
Mol. Mass.:
242.2732
SMILES:
COc1ccc(NC(=O)Cc2ccccc2)cn1
Structure:
Search PDB for entries with ligand similarity: