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Target
D1 dopamine receptor
Ligand
BDBM50010685
Substrate
n/a
Ki
20.2±n/a nM
Comments
PDSP_664
Citation
 Watts, VJ; Lawler, CP; Gilmore, JH; Southerland, SB; Nichols, DE; Mailman, RB Dopamine D1 receptors: efficacy of full (dihydrexidine) vs. partial (SKF38393) agonists in primates vs. rodents. Eur J Pharmacol 242:165-72 (1993) [PubMed]  Article 
Target
Name:
D1 dopamine receptor
Synonyms:
D1 dopamine receptor | DOPAMINE D1 | DRD1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
8818.33
Organism:
Monkey
Description:
Q5I6B7
Residue:
78
Sequence:
VIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPA
  
Inhibitor
Name:
BDBM50010685
Synonyms:
(+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine | (6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | CHEMBL43345 | Dihydrexidine, DHX
Type:
Small organic molecule
Emp. Form.:
C17H17NO2
Mol. Mass.:
267.3224
SMILES:
Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O
Structure:
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