Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Ligand
BDBM84461
Substrate
n/a
Meas. Tech.
Inhibiton Activity Assay
Ki
9.7±0.5 nM
IC50
17±1 nM
Citation
Brik, A; Muldoon, J; Lin, YC; Elder, JH; Goodsell, DS; Olson, AJ; Fokin, VV; Sharpless, KB; Wong, CH Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors. Chembiochem 4:1246-8 (2003) [PubMed] Article
More Info.:
Target
Name:
Gag-Pol polyprotein [489-587,G537V,H558K,V571A]
Synonyms:
HIV-1 protease | HIV-1 protease (G48V) | HIV-1 protease (V82A) | POL_HV1N5 | gag-pol
Type:
Protein
Mol. Mass.:
10827.77
Organism:
Human immunodeficiency virus
Description:
P12497[489-587,G537V,H558K,V571A]
Residue:
99
Sequence:
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIVGIGGFIKVRQYDQILIEICGKKAIGTVLVGPTPANIIGRNLLTQIGCTLNF