Reaction Details Report a problem with these data
Target
G-protein coupled receptor 84
Ligand
BDBM50245499
Substrate
n/a
Meas. Tech.
ChEMBL_1674753 (CHEMBL4024896)
IC50
10.0±n/a nM
Citation
 Liu, YM; Nepali, K; Liou, JP Idiopathic Pulmonary Fibrosis: Current Status, Recent Progress, and Emerging Targets. J Med Chem 60:527-553 (2017) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 84
Synonyms:
EX33 | G-protein coupled receptor 84 | GPR84 | GPR84_HUMAN | Inflammation-related G-protein coupled receptor EX33
Type:
PROTEIN
Mol. Mass.:
43726.73
Organism:
Homo sapiens (Human)
Description:
ChEMBL_116040
Residue:
396
Sequence:
MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
  
Inhibitor
Name:
BDBM50245499
Synonyms:
CHEMBL4085616
Type:
Small organic molecule
Emp. Form.:
C26H21N3O4
Mol. Mass.:
439.4626
SMILES:
O=c1cc(OCC2COc3ncccc3O2)cc2-c3ccc(cc3CCn12)-c1cccnc1
Structure:
Search PDB for entries with ligand similarity: