Reaction Details Report a problem with these data
Target
G-protein coupled receptor 84
Ligand
BDBM50245516
Substrate
n/a
Meas. Tech.
ChEMBL_1674753 (CHEMBL4024896)
IC50
10.0±n/a nM
Citation
 Liu, YM; Nepali, K; Liou, JP Idiopathic Pulmonary Fibrosis: Current Status, Recent Progress, and Emerging Targets. J Med Chem 60:527-553 (2017) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 84
Synonyms:
EX33 | G-protein coupled receptor 84 | GPR84 | GPR84_HUMAN | Inflammation-related G-protein coupled receptor EX33
Type:
PROTEIN
Mol. Mass.:
43726.73
Organism:
Homo sapiens (Human)
Description:
ChEMBL_116040
Residue:
396
Sequence:
MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
  
Inhibitor
Name:
BDBM50245516
Synonyms:
CHEMBL4090321
Type:
Small organic molecule
Emp. Form.:
C25H22N2O5
Mol. Mass.:
430.4526
SMILES:
OCCC#Cc1ccc-2c(CCn3c-2cc(OCC2COc4ncccc4O2)cc3=O)c1
Structure:
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