Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50273118
Substrate
n/a
Meas. Tech.
ChEMBL_1712827 (CHEMBL4122876)
Ki
418±n/a nM
Citation
 Boulahjar, R; Rincon Arias, A; Bolteau, R; Renault, N; Coevoet, M; Barczyk, A; Duroux, R; Yous, S; Melnyk, P; Agouridas, L Design and synthesis of 2,6-disubstituted-8-amino imidazo[1,2a]pyridines, a promising privileged structure. Bioorg Med Chem 26:3296-3307 (2018) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50273118
Synonyms:
CHEMBL4128825
Type:
Small organic molecule
Emp. Form.:
C17H13N3O
Mol. Mass.:
275.3046
SMILES:
Nc1cc(cn2cc(nc12)-c1ccccc1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: