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Target
Oxytocin receptor
Ligand
BDBM50032907
Substrate
n/a
Meas. Tech.
ChEMBL_1724076 (CHEMBL4139354)
IC50
<10000±n/a nM
Citation
 Katte, TA; Reekie, TA; Werry, EL; Jorgensen, WT; Boyd, R; Wong, ECN; Gulliver, DW; Connor, M; Kassiou, M Investigation of pyrazolo-sulfonamides as putative small molecule oxytocin receptor agonists. Eur J Med Chem 136:330-333 (2017) [PubMed]  Article 
Target
Name:
Oxytocin receptor
Synonyms:
OT-R | OXTR | OXYR_HUMAN | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42793.26
Organism:
Homo sapiens (Human)
Description:
Oxytocin OXTR HEK293::B2R9L7
Residue:
389
Sequence:
MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
  
Inhibitor
Name:
BDBM50032907
Synonyms:
CHEMBL3342790
Type:
Small organic molecule
Emp. Form.:
C15H11F3N4O2S
Mol. Mass.:
368.334
SMILES:
FC(F)(F)c1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccn1
Structure:
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