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Target
Vasopressin V1a receptor
Ligand
BDBM50032908
Substrate
n/a
Meas. Tech.
ChEMBL_1724088 (CHEMBL4139366)
EC50
0.125893±n/a nM
Citation
 Katte, TA; Reekie, TA; Werry, EL; Jorgensen, WT; Boyd, R; Wong, ECN; Gulliver, DW; Connor, M; Kassiou, M Investigation of pyrazolo-sulfonamides as putative small molecule oxytocin receptor agonists. Eur J Med Chem 136:330-333 (2017) [PubMed]  Article 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM50032908
Synonyms:
CHEMBL3342789
Type:
Small organic molecule
Emp. Form.:
C14H11ClN4O2S
Mol. Mass.:
334.781
SMILES:
Clc1ccc(cc1)S(=O)(=O)Nc1ccnn1-c1ccccn1
Structure:
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