Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50186426
Substrate
n/a
Meas. Tech.
ChEMBL_1753751 (CHEMBL4188511)
IC50
79000±n/a nM
Citation
Kok, T; Wapenaar, H; Wang, K; Neochoritis, CG; Zarganes-Tzitzikas, T; Proietti, G; Eleftheriadis, N; Kurpiewska, K; Kalinowska-T?u?cik, J; Cool, RH; Poelarends, GJ; Dömling, A; Dekker, FJ Discovery of chromenes as inhibitors of macrophage migration inhibitory factor. Bioorg Med Chem 26:999-1005 (2018) [PubMed] Article
More Info.:
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA