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Target
Sialidase-1
Ligand
BDBM50465984
Substrate
n/a
Meas. Tech.
ChEMBL_1789504 (CHEMBL4261238)
Ki
53±n/a nM
Citation
 Guo, T; Héon-Roberts, R; Zou, C; Zheng, R; Pshezhetsky, AV; Cairo, CW Selective Inhibitors of Human Neuraminidase 1 (NEU1). J Med Chem 61:11261-11279 (2018) [PubMed]  Article 
Target
Name:
Sialidase-1
Synonyms:
NANH | NEU1 | NEUR1_HUMAN | Sialidase 1
Type:
PROTEIN
Mol. Mass.:
45463.28
Organism:
Homo sapiens (Human)
Description:
ChEMBL_960639
Residue:
415
Sequence:
MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
  
Inhibitor
Name:
BDBM50465984
Synonyms:
CHEMBL4278858
Type:
Small organic molecule
Emp. Form.:
C19H23N5O8
Mol. Mass.:
449.4146
SMILES:
[H][C@]1(OC(=C[C@H](O)[C@H]1NC(=O)Cn1cc(nn1)-c1ccc(N)cc1)C(O)=O)[C@H](O)[C@H](O)CO |r,c:3|
Structure:
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