Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50025573
Substrate
n/a
Meas. Tech.
ChEBML_27755
Ki
14000±n/a nM
Citation
 Daly, JW; Padgett, WL; Shamim, MT Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors. J Med Chem 29:1305-8 (1987) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_CAVPO | ADENOSINE A2 | ADORA2A | Adenosine A2a receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44955.08
Organism:
GUINEA PIG
Description:
ADENOSINE A2 0 GUINEA PIG::P46616
Residue:
409
Sequence:
MSSSVYITVELVIAVLAILGNVLVCWAVWINSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLTITIDRYIAIRIPLRYNGLVTCTRAKGIIAICWVLSFAIGLTPMLGWNNCSQPKGDKNHSESCDEGQVTCLFEDVVPMNYMVYYNFFAFVLVPLLLMLGIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHPAKSLAIIVGLFALCCLPLNIINCFTFFCPECDHAPPWLMYLTIILSHGNSVVNPLIYAYRIREFRQTFRKIIRSHILRRRELFKAGGTSARASAAHSPEGEQVSLRLNGHPPGVWANGSALRPEQRPNGYVLGLVSGRSAQRSHGDASLSDVELLSHEHKGTCPESPSLEDPPAHGGAGVS
  
Inhibitor
Name:
BDBM50025573
Synonyms:
1,3-Dibenzyl-3,7-dihydro-purine-2,6-dione | CHEMBL24774
Type:
Small organic molecule
Emp. Form.:
C19H16N4O2
Mol. Mass.:
332.3559
SMILES:
O=c1n(Cc2ccccc2)c2nc[nH]c2c(=O)n1Cc1ccccc1
Structure:
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