Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50025576
Substrate
n/a
Meas. Tech.
ChEBML_28843
Ki
12000±n/a nM
Citation
 Daly, JW; Padgett, WL; Shamim, MT Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors. J Med Chem 29:1305-8 (1987) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50025576
Synonyms:
1,3-Dimethyl-7-prop-2-ynyl-3,7-dihydro-purine-2,6-dione | CHEMBL24049
Type:
Small organic molecule
Emp. Form.:
C10H10N4O2
Mol. Mass.:
218.212
SMILES:
Cn1c2ncn(CC#C)c2c(=O)n(C)c1=O
Structure:
Search PDB for entries with ligand similarity: