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Target
Adenylate kinase 2, mitochondrial
Ligand
BDBM50027422
Substrate
n/a
Meas. Tech.
ChEMBL_32202 (CHEMBL648981)
Ki
1100000±n/a nM
Citation
 Hampton, A; Patel, AD; Maeda, M; Hai, TT; Chang, CD; Kang, JB; Kappler, F; Abo, M; Preston, RK Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 3. Synthesis of adenosine 5'-triphosphate derivatives with N6- or 8-substituents bearing iodoacetyl groups. J Med Chem 25:373-81 (1982) [PubMed]  Article 
Target
Name:
Adenylate kinase 2, mitochondrial
Synonyms:
2.7.4.3 | AK 2 | ATP-AMP transphosphorylase 2 | ATP:AMP phosphotransferase | Adenylate kinase 2 | Adenylate kinase 2, mitochondrial | Adenylate monophosphate kinase | Ak2 | KAD2_RAT
Type:
n/a
Mol. Mass.:
26380.21
Organism:
Rattus norvegicus
Description:
n/a
Residue:
239
Sequence:
MAPNALAPEPEHPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSKATCKDLVMFV
  
Inhibitor
Name:
BDBM50027422
Synonyms:
1N-{4-[9-(3,4-dihydroxy-5-hydroxymethyltetrahydro-2-furanyl)-9H-6-purinyl(methyl)amino]butyl}-1N-methylacetamide 5'-Triphosphate | CHEMBL2367949
Type:
Small organic molecule
Emp. Form.:
C18H31N6O14P3
Mol. Mass.:
648.3918
SMILES:
CN(CCCCN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C(C)=O
Structure:
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