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Target
Melatonin receptor type 1A
Ligand
BDBM50011349
Substrate
n/a
Meas. Tech.
ChEMBL_304031 (CHEMBL840209)
Ki
6.2±n/a nM
Citation
 Lucini, V; Pannacci, M; Scaglione, F; Fraschini, F; Rivara, S; Mor, M; Bordi, F; Plazzi, PV; Spadoni, G; Bedini, A; Piersanti, G; Diamantini, G; Tarzia, G Tricyclic alkylamides as melatonin receptor ligands with antagonist or inverse agonist activity. J Med Chem 47:4202-12 (2004) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50011349
Synonyms:
CHEMBL189449
Type:
Small organic molecule
Emp. Form.:
C19H21NO2
Mol. Mass.:
295.3755
SMILES:
COc1ccc2Cc3ccccc3CC(CNC(C)=O)c2c1
Structure:
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