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Target
Serine/threonine-protein kinase 25
Ligand
BDBM50501882
Substrate
n/a
Meas. Tech.
ChEMBL_1805768 (CHEMBL4305127)
IC50
>10000±n/a nM
Citation
 Liu, X; Wang, B; Chen, C; Qi, Z; Zou, F; Wang, J; Hu, C; Wang, A; Ge, J; Liu, Q; Yu, K; Hu, Z; Jiang, Z; Wang, W; Wang, L; Wang, W; Ren, T; Bai, M; Liu, Q; Liu, J Discovery of ( E)- N J Med Chem 62:5006-5024 (2019) [PubMed]  Article 
Target
Name:
Serine/threonine-protein kinase 25
Synonyms:
SOK1 | STK25 | STK25_HUMAN | YSK1
Type:
PROTEIN
Mol. Mass.:
48113.10
Organism:
Homo sapiens (Human)
Description:
ChEMBL_586495
Residue:
426
Sequence:
MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYKRWKSEGHGEESSSEDSDIDGEAEDGEQGPIWTFPPTIRPSPHSKLHKGTALHSSQKPAEPVKRQPRSQCLSTLVRPVFGELKEKHKQSGGSVGALEELENAFSLAEESCPGISDKLMVHLVERVQRFSHNRNHLTSTR
  
Inhibitor
Name:
BDBM50501882
Synonyms:
CHEMBL4446361
Type:
Small organic molecule
Emp. Form.:
C23H18FN5O2
Mol. Mass.:
415.4197
SMILES:
Fc1cccc(NC(=O)CC(=O)Nc2ccc3c(\C=C\c4ccccn4)n[nH]c3c2)c1
Structure:
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