Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50492051
Substrate
n/a
Meas. Tech.
ChEMBL_964094 (CHEMBL2394447)
Ki
>10000±n/a nM
Citation
 Inamdar, GS; Pandya, AN; Thakar, HM; Sudarsanam, V; Kachler, S; Sabbadin, D; Moro, S; Klotz, KN; Vasu, KK New insight into adenosine receptors selectivity derived from a novel series of [5-substituted-4-phenyl-1,3-thiazol-2-yl] benzamides and furamides. Eur J Med Chem 63:924-34 (2013) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50492051
Synonyms:
CHEMBL2391840
Type:
Small organic molecule
Emp. Form.:
C23H17N3O3S
Mol. Mass.:
415.464
SMILES:
COc1ccc(cc1)C(=O)Nc1nc(c(s1)C(=O)c1ccccn1)-c1ccccc1
Structure:
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