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Target
Delta-type opioid receptor
Ligand
BDBM50166066
Substrate
n/a
Meas. Tech.
ChEMBL_145887 (CHEMBL754253)
IC50
3690±n/a nM
Citation
 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW A topochemical approach to explain morphiceptin bioactivity. J Med Chem 36:708-19 (1993) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50166066
Synonyms:
CHEMBL362991 | H-Tyr-Pro-Phe-Pro-NH2 | MORPHICEPTIN | Tyr-Pro-Phe-Pro-NH2 | [D-Pro4]morphiceptin
Type:
Small organic molecule
Emp. Form.:
C28H35N5O5
Mol. Mass.:
521.608
SMILES:
N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O |r|
Structure:
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