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Target
Protein Rev
Ligand
BDBM50248131
Substrate
n/a
Meas. Tech.
ChEMBL_1811902 (CHEMBL4311362)
IC50
6000±n/a nM
Citation
 Simon, B; Walmsley, C; Jackson, VJ; Garvey, EP; Slater, MJ; Berrisford, DJ; Gardiner, JM Evaluation of neomycin analogues for HIV-1 RRE RNA recognition identifies enhanced activity simplified neamine analogues. Bioorg Med Chem Lett 29:339-341 (2019) [PubMed]  Article 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM50248131
Synonyms:
CHEMBL3754093
Type:
Small organic molecule
Emp. Form.:
C23H46N6O13
Mol. Mass.:
614.6437
SMILES:
[H]C1(OC2C(O)C(N)CC(N)C2OC2([H])OC(CN)C(O)C(O)C2N)OC(CO)C(OC2([H])OC(CN)C(O)C(O)C2N)C1O
Structure:
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