Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50519773
Substrate
n/a
Meas. Tech.
ChEMBL_1878368 (CHEMBL4379762)
Ki
9160±n/a nM
Citation
 Matos, MJ; Vilar, S; Vazquez-Rodriguez, S; Kachler, S; Klotz, KN; Buccioni, M; Delogu, G; Santana, L; Uriarte, E; Borges, F Structure-Based Optimization of Coumarin hA J Med Chem 63:2577-2587 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50519773
Synonyms:
CHEMBL4553497
Type:
Small organic molecule
Emp. Form.:
C15H10O5
Mol. Mass.:
270.2369
SMILES:
Oc1ccc(cc1)-c1cc2ccc(O)c(O)c2oc1=O
Structure:
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