Reaction Details Report a problem with these data
Target
Retinoic acid receptor gamma
Ligand
BDBM50075366
Substrate
n/a
Meas. Tech.
ChEBML_196323
Kd
>0.001000±n/a nM
Citation
 Vuligonda, V; Garst, ME; Chandraratna, RA Stereoselective synthesis and receptor activity of conformationally defined retinoid X receptor selective ligands. Bioorg Med Chem Lett 9:589-94 (1999) [PubMed]  Article 
Target
Name:
Retinoic acid receptor gamma
Synonyms:
NR1B3 | Nuclear receptor subfamily 1 group B member 3 | RAR-gamma | RARG | RARG_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoic acid receptor gamma | Retinoid receptor
Type:
PROTEIN
Mol. Mass.:
50345.43
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458016
Residue:
454
Sequence:
MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
  
Inhibitor
Name:
BDBM50075366
Synonyms:
(2E,4E)-3-Methyl-5-{2-[(E)-2-(2,6,6-trimethyl-cyclohex-1-enyl)-vinyl]-phenyl}-penta-2,4-dienoic acid | CHEMBL157333
Type:
Small organic molecule
Emp. Form.:
C23H28O2
Mol. Mass.:
336.4672
SMILES:
C\C(\C=C\c1ccccc1\C=C\C1=C(C)CCCC1(C)C)=C/C(O)=O |c:13|
Structure:
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