Reaction Details Report a problem with these data
Target
Monoglyceride lipase
Ligand
BDBM50479142
Substrate
n/a
Meas. Tech.
ChEMBL_1922151 (CHEMBL4424996)
Ki
>100000±n/a nM
Citation
 Cunningham, CW Plant-Based Modulators of Endocannabinoid Signaling. J Nat Prod 82:636-646 (2019) [PubMed]  Article 
Target
Name:
Monoglyceride lipase
Synonyms:
HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN
Type:
Hydrolase
Mol. Mass.:
33264.56
Organism:
Homo sapiens (Human)
Description:
Human recombinant MGL (Cayman Chemical, cat# 10008354).
Residue:
303
Sequence:
MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTASPP
  
Inhibitor
Name:
BDBM50479142
Synonyms:
Guineensine | Guineesine | Pipyahyine
Type:
Small organic molecule
Emp. Form.:
C24H33NO3
Mol. Mass.:
383.5237
SMILES:
CC(C)CNC(=O)\C=C\C=C\CCCCCC\C=C\c1ccc2OCOc2c1
Structure:
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