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Target
D(2) dopamine receptor
Ligand
BDBM50096740
Substrate
n/a
Meas. Tech.
ChEBML_61456
Ki
541±n/a nM
Citation
 Linnanen, T; Brisander, M; Mohell, N; Johansson, AM Serotonergic and dopaminergic activities of rigidified (R)-aporphine derivatives. Bioorg Med Chem Lett 11:367-70 (2001) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50096740
Synonyms:
(R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-benzo[cd]pyren-1-one | CHEMBL122485
Type:
Small organic molecule
Emp. Form.:
C18H15NO2
Mol. Mass.:
277.3172
SMILES:
CN1CCc2ccc3c4c2[C@H]1Cc1cccc(oc3=O)c41
Structure:
Search PDB for entries with ligand similarity: