Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50566373
Substrate
n/a
Meas. Tech.
ChEMBL_2100237 (CHEMBL4808633)
EC50
0.417000±n/a nM
Citation
 Zhao, X; Yoon, DO; Yoo, J; Park, HJ Structure-Activity Relationship Study and Biological Evaluation of 2-(Disubstituted phenyl)-indole-5-propanoic Acid Derivatives as GPR40 Full Agonists. J Med Chem 64:4130-4149 (2021) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50566373
Synonyms:
CHEMBL4847662
Type:
Small organic molecule
Emp. Form.:
C19H19NO2
Mol. Mass.:
293.3597
SMILES:
Cc1ccc(C)c(c1)-c1cc2cc(CCC(O)=O)ccc2[nH]1
Structure:
Search PDB for entries with ligand similarity: