Reaction Details Report a problem with these data
Target
Peptide deformylase
Ligand
BDBM50131892
Substrate
n/a
Meas. Tech.
ChEMBL_154316 (CHEMBL762801)
Ki
0.67±n/a nM
Citation
 Hu, X; Nguyen, KT; Verlinde, CL; Hol, WG; Pei, D Structure-based design of a macrocyclic inhibitor for peptide deformylase. J Med Chem 46:3771-4 (2003) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2
Type:
n/a
Mol. Mass.:
16901.39
Organism:
Escherichia coli
Description:
n/a
Residue:
150
Sequence:
MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIGLRLGNGKYCTLRLFFNQV
  
Inhibitor
Name:
BDBM50131892
Synonyms:
CHEMBL421252 | N-(3-tert-Butyl-2,5-dioxo-1,4diaza-cyclopentadec-6-ylmethyl)-N-hydroxy-formamide
Type:
Small organic molecule
Emp. Form.:
C19H35N3O4
Mol. Mass.:
369.4989
SMILES:
CC(C)(C)[C@@H]1NC(=O)C(CN(O)C=O)CCCCCCCCCNC1=O
Structure:
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