Reaction Details Report a problem with these data
Target
Methionine aminopeptidase 2
Ligand
BDBM50137354
Substrate
n/a
Meas. Tech.
ChEBML_105144
Ki
600000±n/a nM
Citation
 Hu, X; Zhu, J; Srivathsan, S; Pei, D Peptidyl hydroxamic acids as methionine aminopeptidase inhibitors. Bioorg Med Chem Lett 14:77-9 (2003) [PubMed]  Article 
Target
Name:
Methionine aminopeptidase 2
Synonyms:
Initiation factor 2-associated 67 kDa glycoprotein | MAP 2 | MAP2_HUMAN | METAP2 | MNPEP | MetAP 2 | Methionine aminopeptidase 2 (MetAP2) | Methionine aminopeptidases (HsMetAP2) | P67EIF2 | Peptidase M 2 | p67
Type:
Enzyme
Mol. Mass.:
52884.45
Organism:
Homo sapiens (Human)
Description:
P50579
Residue:
478
Sequence:
MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
  
Inhibitor
Name:
BDBM50137354
Synonyms:
CHEMBL164406 | [((R)-2-Amino-propionyl)-hydroxy-amino]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C5H10N2O4
Mol. Mass.:
162.1439
SMILES:
C[C@@H](N)C(=O)N(O)CC(O)=O
Structure:
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