Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM50139372
Substrate
n/a
Meas. Tech.
ChEBML_60859
Ki
290000±n/a nM
Citation
 Park, J; Fu, H; Pei, D Peptidyl aldehydes as slow-binding inhibitors of dual-specificity phosphatases. Bioorg Med Chem Lett 14:685-7 (2004) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM50139372
Synonyms:
4-((S)-(S)-1-Carbamoyl-3-carboxy-propylcarbamoyl)-4-{2-[4-(3-oxo-propenyl)-benzoylamino]-acetylamino}-butyric acid | CHEMBL351423
Type:
Small organic molecule
Emp. Form.:
C22H26N4O9
Mol. Mass.:
490.4632
SMILES:
NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)c1ccc(\C=C\C=O)cc1
Structure:
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