Reaction Details
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Target
ATP synthase subunit beta,/delta,/epsilon,/gamma, mitochondrial
Ligand
BDBM50404306
Substrate
n/a
Meas. Tech.
ChEMBL_65930 (CHEMBL679205)
IC50
2138±n/a nM
Citation
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More Info.:
Target
Name:
ATP synthase subunit beta,/delta,/epsilon,/gamma, mitochondrial
Synonyms:
Mitochondrial complex V; ATP synthase
Type:
n/a
Mol. Mass.:
n/a
Description:
ASSAY_ID of EBI is 65924
Components:
This complex has 4 components.
Component 1
Name:
ATP synthase subunit epsilon, mitochondrial
Synonyms:
ATP5E | ATP5E_BOVIN | ATP5F1E | ATPase subunit epsilon
Type:
PROTEIN
Mol. Mass.:
5790.87
Organism:
Bos taurus
Description:
EBI_100264
Residue:
51
Sequence:
MVAYWRQAGLSYIRYSQICAKAVRDALKTEFKANAMKTSGSTIKIVKVKKE
Component 2
Name:
ATP synthase subunit beta, mitochondrial
Synonyms:
ATP5B | ATP5F1B | ATPB_BOVIN
Type:
PROTEIN
Mol. Mass.:
56271.25
Organism:
Bos taurus
Description:
EBI_100264
Residue:
528
Sequence:
MLGLVGRVVAASASGALRGLSPSAPLPQAQLLLRAAPAALQPARDYAAQASPSPKAGATTGRIVAVIGAVVDVQFDEGLPPILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGAPIRIPVGPETLGRIMNVIGEPIDERGPIKTKQFAAIHAEAPEFVEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQRFLSQPFQVAEVFTGHLGKLVPLKETIKGFQQILAGEYDHLPEQAFYMVGPIEEAVAKADKLAEEHS
Component 3
Name:
ATP synthase subunit gamma, mitochondrial
Synonyms:
ATP5C | ATP5C1 | ATP5F1C | ATPG_BOVIN | F-ATPase gamma subunit
Type:
PROTEIN
Mol. Mass.:
33081.70
Organism:
Bos taurus
Description:
ChEMBL_65923
Residue:
298
Sequence:
MFSRAGVAGLSAWTVQPQWIQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAERELKPARVYGVGSLALYEKADIKTPEDKKKHLIIGVSSDRGLCGAIHSSVAKQMKSEAANLAAAGKEVKIIGVGDKIRSILHRTHSDQFLVTFKEVGRRPPTFGDASVIALELLNSGYEFDEGSIIFNRFRSVISYKTEEKPIFSLDTISSAESMSIYDDIDADVLRNYQEYSLANIIYYSLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAALD
Component 4
Name:
ATP synthase subunit delta, mitochondrial
Synonyms:
ATP5D | ATP5F1D | ATPD_BOVIN | F-ATPase delta subunit
Type:
PROTEIN
Mol. Mass.:
17608.84
Organism:
Bos taurus
Description:
EBI_100264
Residue:
168
Sequence:
MLPSALLRRPGLGRLVRQVRLYAEAAAAQAPAAGPGQMSFTFASPTQVFFNSANVRQVDVPTQTGAFGILAAHVPTLQVLRPGLVVVHAEDGTTSKYFVSSGSVTVNADSSVQLLAEEAVTLDMLDLGAAKANLEKAQSELLGAADEATRAEIQIRIEANEALVKALE