Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50109389
Substrate
n/a
Meas. Tech.
ChEMBL_200962 (CHEMBL802050)
Ki
309±n/a nM
Citation
 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity. J Med Chem 47:2308-17 (2004) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50109389
Synonyms:
1-Phenethyl-piperidine | 1-phenethylpiperidine | CHEMBL75228 | N-(2-phenylethyl)piperidine | N-phenethylpiperidine
Type:
Small organic molecule
Emp. Form.:
C13H19N
Mol. Mass.:
189.2967
SMILES:
C(Cc1ccccc1)N1CCCCC1
Structure:
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