Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50589711
Substrate
n/a
Meas. Tech.
ChEMBL_2194199 (CHEMBL5106559)
Ki
116±n/a nM
Citation
 Mishiro, K; Wang, M; Hirata, S; Fuchigami, T; Shiba, K; Kinuya, S; Ogawa, K Development of tumor-targeting aza-vesamicol derivatives with high affinity for sigma receptors for cancer theranostics. RSC Med Chem 13:986-997 (2022) [PubMed] 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50589711
Synonyms:
CHEMBL5183643
Type:
Small organic molecule
Emp. Form.:
C18H27BrN2O
Mol. Mass.:
367.324
SMILES:
O[C@H]1CCC[C@@H]1N1CCN(CCCc2ccccc2Br)CC1 |r|
Structure:
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