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Target
Gamma-aminobutyric acid receptor subunit beta
Ligand
BDBM50179898
Substrate
n/a
Meas. Tech.
ChEMBL_339397 (CHEMBL866053)
IC50
74±n/a nM
Citation
 Meegalla, SK; Doller, D; Liu, R; Sha, D; Lee, Y; Soll, RM; Wisnewski, N; Silver, GM; Dhanoa, D Synthesis and insecticidal activity of fluorinated 2-(2,6-dichloro-4-trifluoromethylphenyl)-2,4,5,6-tetrahydrocyclopentapyrazoles. Bioorg Med Chem Lett 16:1702-6 (2006) [PubMed]  Article 
Target
Name:
Gamma-aminobutyric acid receptor subunit beta
Synonyms:
GABA receptor subunit | GBRB_MUSDO | Rdl
Type:
PROTEIN
Mol. Mass.:
63660.23
Organism:
Musca domestica
Description:
ChEMBL_339397
Residue:
576
Sequence:
MSDSMLYQTLQTCLPKSRLITLWLAFTLAMLIQEPRRHAATVNAATAGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAVEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVVISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMTIQKMAEQKKQQQLDGVQPPPNPNPNTMVDHGGHGHGHGHHSHGHPHVPKQTVSNRPIGFQTMQQQNIGGRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPPVGPHGPGPQGPPGGPPAGGGGGGAPPEGGDAEAAVPAHLLHPGKVKKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVLLGEEK
  
Inhibitor
Name:
BDBM50179898
Synonyms:
2-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4,4,6,6-tetrafluoro-2,4,5,6-tetrahydrocyclopenta[c]pyrazole | CHEMBL427379
Type:
Small organic molecule
Emp. Form.:
C13H5Cl2F7N2
Mol. Mass.:
393.087
SMILES:
FC(F)(F)c1cc(Cl)c(c(Cl)c1)-n1cc2c(n1)C(F)(F)CC2(F)F
Structure:
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