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Target
Gamma-aminobutyric acid receptor subunit beta
Ligand
BDBM50179908
Substrate
n/a
Meas. Tech.
ChEMBL_339397 (CHEMBL866053)
IC50
100±n/a nM
Citation
 Meegalla, SK; Doller, D; Liu, R; Sha, D; Lee, Y; Soll, RM; Wisnewski, N; Silver, GM; Dhanoa, D Synthesis and insecticidal activity of fluorinated 2-(2,6-dichloro-4-trifluoromethylphenyl)-2,4,5,6-tetrahydrocyclopentapyrazoles. Bioorg Med Chem Lett 16:1702-6 (2006) [PubMed]  Article 
Target
Name:
Gamma-aminobutyric acid receptor subunit beta
Synonyms:
GABA receptor subunit | GBRB_MUSDO | Rdl
Type:
PROTEIN
Mol. Mass.:
63660.23
Organism:
Musca domestica
Description:
ChEMBL_339397
Residue:
576
Sequence:
MSDSMLYQTLQTCLPKSRLITLWLAFTLAMLIQEPRRHAATVNAATAGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAVEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVVISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMTIQKMAEQKKQQQLDGVQPPPNPNPNTMVDHGGHGHGHGHHSHGHPHVPKQTVSNRPIGFQTMQQQNIGGRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPPVGPHGPGPQGPPGGPPAGGGGGGAPPEGGDAEAAVPAHLLHPGKVKKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVLLGEEK
  
Inhibitor
Name:
BDBM50179908
Synonyms:
2-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-fluoro-4-methoxy-4-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazole | CHEMBL206707
Type:
Small organic molecule
Emp. Form.:
C15H12Cl2F4N2O
Mol. Mass.:
383.168
SMILES:
COC1(C)C(F)Cc2nn(cc12)-c1c(Cl)cc(cc1Cl)C(F)(F)F
Structure:
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