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Target
Gamma-aminobutyric acid receptor subunit beta
Ligand
BDBM50179903
Substrate
n/a
Meas. Tech.
ChEMBL_339397 (CHEMBL866053)
IC50
100±n/a nM
Citation
 Meegalla, SK; Doller, D; Liu, R; Sha, D; Lee, Y; Soll, RM; Wisnewski, N; Silver, GM; Dhanoa, D Synthesis and insecticidal activity of fluorinated 2-(2,6-dichloro-4-trifluoromethylphenyl)-2,4,5,6-tetrahydrocyclopentapyrazoles. Bioorg Med Chem Lett 16:1702-6 (2006) [PubMed]  Article 
Target
Name:
Gamma-aminobutyric acid receptor subunit beta
Synonyms:
GABA receptor subunit | GBRB_MUSDO | Rdl
Type:
PROTEIN
Mol. Mass.:
63660.23
Organism:
Musca domestica
Description:
ChEMBL_339397
Residue:
576
Sequence:
MSDSMLYQTLQTCLPKSRLITLWLAFTLAMLIQEPRRHAATVNAATAGGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAVEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVVISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMTIQKMAEQKKQQQLDGVQPPPNPNPNTMVDHGGHGHGHGHHSHGHPHVPKQTVSNRPIGFQTMQQQNIGGRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPPVGPHGPGPQGPPGGPPAGGGGGGAPPEGGDAEAAVPAHLLHPGKVKKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVLLGEEK
  
Inhibitor
Name:
BDBM50179903
Synonyms:
2-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5,5-difluoro-4-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-4-ol | CHEMBL203278
Type:
Small organic molecule
Emp. Form.:
C14H9Cl2F5N2O
Mol. Mass.:
387.132
SMILES:
CC1(O)c2cn(nc2CC1(F)F)-c1c(Cl)cc(cc1Cl)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: