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Target
Integrase
Ligand
BDBM50197646
Substrate
n/a
Meas. Tech.
ChEMBL_432311 (CHEMBL915571)
IC50
>100000±n/a nM
Citation
 Meadows, DC; Sanchez, T; Neamati, N; North, TW; Gervay-Hague, J Ring substituent effects on biological activity of vinyl sulfones as inhibitors of HIV-1. Bioorg Med Chem 15:1127-37 (2006) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50197646
Synonyms:
CHEMBL375883 | bis(1-benzyloxy-trans-2-(2-methanesulfonyl-vinyl)-benzene)
Type:
Small organic molecule
Emp. Form.:
C31H28O6S2
Mol. Mass.:
560.68
SMILES:
O=S(=O)(CS(=O)(=O)\C=C\c1ccccc1OCc1ccccc1)\C=C\c1ccccc1OCc1ccccc1
Structure:
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